Benefits

Oligopin Maritime Pine†

French maritime pine bark extract (FMPBE) contains oligomeric procyanidins (OPC), a specific type of flavonoid showing strong antioxidant properties which help support healthy levels of circulating oxLDL.8 Oligopin (OP) is a standardized FMPBE with a unique profile characterized by high concentration of OPC and an absence of tannins, resulting in improved bioavailability.8,9 In a randomized, double-blind, placebo-controlled crossover trial consisting of 24 participants, 150 mg of OP supported many aspects of cardiometabolic health including maintaining healthy levels of both HDL-C and ApoB/A1 ratios, as well as supporting plasma oxLDL levels already within the normal range.

MEDITEANOXTM Olive Fruit Extract†

Olive oil possess naturally occurring phenolic compounds that have been investigated for their beneficial role in the Mediterranean diet’s ability to maintain arterial and cardiometabolic health.10-14 MEDITEANOXTM is an olive fruit extract standardized for hydroxytyrosol (HT), one of the olive’s primary polyphenols with potent antioxidant effects, with animal and invitro studies showing its ability to support cardiometabolic health.15 Human pilot intervention studies using MEDITEANOXTM show beneficial effects in supporting healthy plasma oxLDL levels and antioxidant capacity, as well as supporting optimal cytokine balance.16-18

PomanoxTM Pomegranate Extract†

Pomegranate fruit has been a symbol of health and longevity used by many cultures throughout history, with research now revealing the fruits health promoting properties are due to a unique class of polyphenols called punicalagins (PC).19 PomanoxTM uses a propriety extraction method producing a polyphenol spectrum corresponding to whole fresh pomegranates, enabling natural synergy between PC and other pomegranate polyphenols which helps maintain cardiovascular health.19,20 Mechanistically, pomegranate PCs are able to support the function of HDL through PON1 activation, as well as activate nitric oxide production by activating the AKT/eNOS axis, supporting endothelial function.21-24 In a clinical trial using both PomanoxTM and MEDITEANOXTM, the authors found HT and PC supported healthy blood pressure, as well as healthy levels of malondialdehyde (MDA) and oxLDL.25