HPA ADAPT ( 120 caps) by Godby Naturopathic

Ingredients

Holy Basil

Holy basil (Ocimum sanctum) is an adaptogenic herb that enhances the body’s stress and immune response. A comprehensive review of 24 human studies has revealed positive therapeutic effects of holy basil on neurocognition, immunity and metabolism.1 Thirty-five subjects were dosed with Ocimum sanctum, and it was found to have a statistically significant effect on low mood and attention.2

Ashwagandha Root Extract†

Ashwagandha’s strong adaptogenic properties provide an array of benefits for individuals who have compromised health due to extreme stress exposure. Ashwagandha’s benefits include improving stress resilience, supporting immune response, regulating the sleep cycle, supporting the healthy thyroid function and protecting against exhaustion of the nervous system.3,4 Ashwagandha has also been shown to be beneficial in supporting proper mood regulation and restoring a sense of calmness under stress.4

Rhodiola rosea Root Extract†

Rhodiola rosea has been categorized as an adaptogenic botanical due to its ability to increase resistance to a variety of stressors.5 Rhodiola has been studied extensively and is widely used in Eastern Europe and Asia to help support the nervous system, mood regulation, mental clarity, work performance and the sleep cycle.5 Within the central nervous system, Rhodiola has demonstrated an ability to preserve levels of neurotransmitters, such as serotonin, dopamine and norepinephrine. In a randomized, double-blind, placebo-
controlled study examining the effects of Rhodiola on fatigue and stress, 161 patients aged 19 to 21 years received 185 mg of Rhodiola twice daily and saw a significant reduction in fatigue.6 An additional study using Rhodiola extract in students showed significant improvements in mental performance, greater mood stability and improved sleep patterns.7

Eleuthero Root Extract†

Eleutherococcus senticosus has been identified as a strong adaptogenic botanical and is widely used in China to improve general health and support memory and physical endurance.8 In addition to its ability to improve stress resilience and maintain energy, eleuthero has been shown to support the immune system.9 In a double-blind study, the adaptogenic effects of eleuthero were demonstrated to help maintain a sense of calm, reflected by a reduced heart rate during stress exposure.10 Eleuthero has also been shown to improve
performance in runners. In a study on performance athletes, eleuthero extract (2 or 4 mL) given 30 minutes prior to a race
significantly reduced race time (48.7 minutes) compared to the control group (52.6 minutes).11

Schisandra Berry Extract†

Schisandra is an adaptogenic botanical that has been used for centuries in China and Russia to help support mental clarity,
stress response and emotional wellness. In a double-blind, placebo-controlled study, athletes were given Schisandra chinensis and Bryonia alba extracts or placebo. Those receiving the therapy had increased concentrations of nitric oxide, a molecule that causes the blood vessels to expand, resulting in increased circulation, blood flow and nutrients throughout the body.12 The researchers concluded that schisandra provides supportive factors for physical performance in athletes.12 Schisandra berry has been shown to support learning and memory and may have some protective factors that support brain health.13

Licorice Root Extract†

The primary components in licorice root that support adrenal health include glycyrrhetinic acid and glycyrrhizin. Licorice has also been shown to block 11-β-hydroxysteroid dehydrogenase, the enzyme responsible for the conversion of cortisol to the inactive cortisone. When taken in small doses, licorice root extract can be used to maintain normal cortisol levels, an important factor for individuals that need to support adrenal hormone production and maintain healthy inflammatory pathways.14